Dissecting cell membrane tension dynamics and its effect on Piezo1-mediated cellular mechanosensitivity using force-controlled nanopipettes

for journal club Dissecting cell membrane tension dynamics and its effect on Piezo1-mediated cellular mechanosensitivity using force-controlled nanopipettes | Nature Methods #Piezo1AFMPatchclampCal520

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reading the article

questions

1. Figure 1e last red image why blacked? no idea, the indentation force is the same for both cells
2. It could also be cell nanotubes for the membrane rupture induced surrounding Ca events

general questions

Fluid FM benefits

controlled indentation force